Released on the Action 52 cartridge, The Cheetahmen was Active Enterprises' attempt to compete with the success of franchises such as Battletoads and Teenage Mutant Ninja Turtles. The Action 52 cartridge came with a twelve-page comic book providing the Cheetahmen's backstory.
The Cheetahmen consists of six levels, two for each of the three Cheetahmen. The second level includes a boss battle. Other than the bosses, all of the other enemies are characters from the other games, including Saddam Hussein parody Satán Hossain from Storm over the Desert, a simple overhead tank game where running over Hossain, who appears very frequently, gives the player another life.
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