Abdoul Karim Sylla (born 10 January 1981 in Fria) is a Guinean football player.
Sylla previously played for KSC Lokeren in the Belgian First Division and Diyarbakirspor in the Turkish Super Lig.
He was part of the Guinean 2004 African Nations Cup team, who finished second in their group in the first round of competition, before losing in the quarter finals to Mali.