Schedule
| Date | Time | Opponent# | Rank# | Site | TV | Result | Attendance | |
|---|---|---|---|---|---|---|---|---|
| September 6 | 12:00 PM | Northern Colorado* | Ross–Ade Stadium • West Lafayette, IN | BTN | W 42–10 | 51,476 | ||
| September 13 | 3:30 PM | #14 Oregon* | Ross–Ade Stadium • West Lafayette, IN | ABC | L 26–32 2OT | 54,666 | ||
| September 20 | 12:00 PM | Central Michigan* | Ross–Ade Stadium • West Lafayette, IN | BTN | W 32–25 | 57,101 | ||
| September 27 | 3:30 PM | at Notre Dame* | Notre Dame Stadium • Notre Dame, IN (Shillelagh Trophy) | NBC | L 38–21 | 80,795 | ||
| October 4 | 12:00 PM | #6 Penn State | Ross–Ade Stadium • West Lafayette, IN | ESPN | L 20–6 | 57,215 | ||
| October 11 | 3:30 PM | at #11 Ohio State | Ohio Stadium • Columbus, OH | ABC | L 16–3 | 105,378 | ||
| October 18 | 12:00 PM | at Northwestern | Ryan Field • Evanston, IL | ESPN2 | L 26–48 | 27,163 | ||
| October 25 | 12:00 PM | #25 Minnesota | Ross–Ade Stadium • West Lafayette, IN | ESPNC | L 6–17 | 54,215 | ||
| November 1 | 12:00 PM | Michigan | Ross–Ade Stadium • West Lafayette, IN | BTN | W 48–42 | 59,135 | ||
| November 8 | 12:00 PM | at #17 Michigan State | Spartan Stadium • East Lansing, MI | BTN | L 7–21 | 75,522 | ||
| November 15 | 12:00 PM | at Iowa | Kinnick Stadium • Iowa City, IA | BTN | L 17-22 | 67,676 | ||
| November 22 | 12:00 PM | Indiana | Ross–Ade Stadium • West Lafayette, IN (Old Oaken Bucket) | ESPN2 | W 62-10 | 63,107 | ||
Read more about this topic: 2008 Purdue Boilermakers Football Team