Schedule
| Date | Time | Opponent# | Rank# | Site | TV | Result | Attendance | |
|---|---|---|---|---|---|---|---|---|
| August 30 | 12:00 PM | vs. #17 Virginia Tech* | Bank of America Stadium • Charlotte, NC | ESPN | W 27-22 | 72,169 | ||
| September 6 | 4:30 PM | #8 West Virginia* | Dowdy-Ficklen Stadium • Greenville, NC | ESPN | W 24-3 | 43,610 | ||
| September 13 | 3:00 PM | at Tulane | #14 | Louisiana Superdome • New Orleans, LA | WITN-TV | W 28-24 | 27,189 | |
| September 20 | 12:00 PM | at North Carolina State* | #15 | Carter-Finley Stadium • Raleigh, NC (ECU – NC State rivalry) | ESPN | L 30-24 OT | 57,583 | |
| September 27 | 3:30 PM | Houston | #23 | Dowdy-Ficklen Stadium • Greenville, NC | CBSCS | L 41-24 | 43,641 | |
| October 11 | 12:00 PM | at Virginia* | Scott Stadium • Charlottesville, VA | LFS | L 20-35 | 52,398 | ||
| October 18 | 12:00 PM | Memphis | Dowdy-Ficklen Stadium • Greenville, NC | WITN-TV/CSS | W 30-10 | 41,216 | ||
| November 2 | 8:00 PM | at UCF | Bright House Networks Stadium • Orlando, FL | ESPN | W 13-10 OT | 40,202 | ||
| November 8 | 3:30 PM | Marshall | Dowdy-Ficklen Stadium • Greenville, NC | CBSCS | W 19-16 OT | 43,515 | ||
| November 15 | 3:00 PM | at Southern Miss | M. M. Roberts Stadium • Hattiesburg, MS | WITN-TV | L 21-3 | 30,658 | ||
| November 22 | 4:00 PM | at UAB | Legion Field • Birmingham, AL | WITN-TV/CSS | W 17-13 | 11,453 | ||
| November 29 | 1:00 PM | UTEP | Dowdy-Ficklen Stadium • Greenville, NC | CBSCS | W 53-21 | 38,098 | ||
| December 6 | 12:00 PM | at Tulsa | Chapman Stadium • Tulsa, OK (C-USA Championship) | ESPN2 | W 27-24 | 22,740 | ||
| January 2 | 4:00 PM | vs. Kentucky* | Liberty Bowl Memorial Stadium • Memphis, TN (Liberty Bowl) | ESPN | L 25-19 | 56,125 | ||
Read more about this topic: 2008 East Carolina Pirates Football Team