2-methyleneglutarate Mutase

In enzymology, a 2-methyleneglutarate mutase (EC 5.4.99.4) is an enzyme that catalyzes the chemical reaction

2-methyleneglutarate 2-methylene-3-methylsuccinate

Hence, this enzyme has one substrate, 2-methyleneglutarate, and one product, 2-methylene-3-methylsuccinate.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. The systematic name of this enzyme class is 2-methyleneglutarate carboxy-methylenemethylmutase. This enzyme is also called alpha-methyleneglutarate mutase. This enzyme participates in c5-branched dibasic acid metabolism. It employs one cofactor, cobamide.