In enzymology, a 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) is an enzyme that catalyzes the chemical reaction
- 2-dehydro-3-deoxy-D-pentonate pyruvate + glycolaldehyde
Hence, this enzyme has one substrate, 2-dehydro-3-deoxy-D-pentonate, and two products, pyruvate and glycolaldehyde.
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxy-D-pentonate aldolase, 3-deoxy-D-pentulosonic acid aldolase, and 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase. This enzyme participates in pentose and glucuronate interconversions.