Offseason
- October 13, 1959: Hal Jeffcoat was released by the Cardinals.
- December 2, 1959: Gene Green and Charles Staniland (minors) were traded by the Cardinals to the Baltimore Orioles for Bob Nieman.
- December 4, 1959: Bill Smith and Bobby Gene Smith were traded by the Cardinals to the Philadelphia Phillies for Carl Sawatski.
Read more about this topic: 1960 St. Louis Cardinals Season