In Transportation
- California State Route 154 runs from Los Olivos to Santa Barbara, California
- Connecticut Route 154 runs from Old Saybrook, to Middletown
- Georgia State Route 154 runs from S.R. 54 in Sharpsburg to S.R. 10
- Illinois Route 154 runs from Red Bud to Whittington in Sullivan County, Indiana
- Indiana State Road 154 runs from Hutsonville, Illinois to Sullivan, Indiana
- M-154 is a Michigan highway on Harsens Island at the mouth of the St. Clair River
- Missouri Route 154 runs from Vandalia to Paris, Missouri
- New Jersey Route 154 runs from County Route 561 to Routes 41 and Route 70
- New York State Route 154 was a state highway in Rensselaer County, New York until 1980
- Ohio State Route 154 in Columbiana County in northeast Ohio runs from Lisbon, Ohio to Negley, Ohio
- Oregon Route 154 is a state highway that runs from Dayton to Hopewell
- Pennsylvania Route 154 is a state highway that runs from Canton to Laporte
- Texas State Highway 154 is a state highway that runs from Cooper to Marshall
- Utah State Route 154 runs from Draper to Salt Lake City International Airport
- Virginia Route 154 is a state highway in Covington, Virginia
- Wisconsin Highway 154 runs from Lloyd to Rock Springs
- Route nationale 154 is a national trunk road in France connecting Rouen and Orléans (Artenay)
- Malaysia Federal Route 154 on Langkawi Island, Kedah, Malaysia
- Route 154 near Alberton in Prince Edward Island, Canada
- National Route 154 is a national highway of Japan connecting Higashi-ku, Nagoya and Atsuta-ku, Nagoya
- Seattle Bus Route 154
- The Maserati Tipo 154 racecar, also known as 151/4, was produced in 1965
- Gol Transportes Aéreos Flight 1907 crashed on September 29, 2006 over the Brazilian state of Mato Grosso killing 154 onboard
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