Yuet Wai Kan - Research

Research

Kan is regarded as a pioneer of applying molecular biology and genetics into clinical medicine. Kan was the first to establish that a single DNA mutation could lead to a human disease, and the first to diagnose a human disease by using DNA.

Kan has made many fundamental contributions to our understanding of human blood diseases. Kan was the first to discover the gene deletion in human alpha-thalassemia; he was the first to discover a point-mutation causing human beta-thalassemia; with Golbus' help, he was the first to carry out prenatal diagnosis (for a haemoglobinopathy).

Kan is best known for his groundbreaking works in sickle cell and thalassemia. He is the first person who used fetal DNA diagnosis techniques to study these diseases. Kan's work led to the innovation of DNA diagnosis.

Kan discovered DNA polymorphism, which nowadays is widely used in genetic analysis for human diseases.

Read more about this topic:  Yuet Wai Kan

Famous quotes containing the word research:

    The research on gender and morality shows that women and men looked at the world through very different moral frameworks. Men tend to think in terms of “justice” or absolute “right and wrong,” while women define morality through the filter of how relationships will be affected. Given these basic differences, why would men and women suddenly agree about disciplining children?
    Ron Taffel (20th century)

    I did my research and decided I just had to live it.
    Karina O’Malley, U.S. sociologist and educator. As quoted in the Chronicle of Higher Education, p. A5 (September 16, 1992)

    To be sure, nothing is more important to the integrity of the universities ... than a rigorously enforced divorce from war- oriented research and all connected enterprises.
    Hannah Arendt (1906–1975)