Willamette ( /wɨlˈlæmɨt/ wil-LAM-it), from the Clackamas language of the Columbia River, Oregon, can refer to:
A toponym of the U.S. state of Oregon:
- Willamette River, a tributary of the Columbia River in northwestern Oregon
- Willamette Valley, a region in northwest Oregon that surrounds the Willamette River
- Willamette Valley AVA, Oregon wine region
- Willamette Valley forests, an ecoregion that includes the Willamette Valley and adjacent parts of Washington
- Willamette, Oregon, an unincorporated community that is now part of West Linn
- Willamette National Forest, a National Forest in western Oregon
- Willamette Falls, a natural waterfall on the Willamette River between Oregon City and West Linn
- Willamette Meteorite, a meteorite that was discovered in Oregon
- Willamette Pass Resort, a ski area in the Cascade Range of Oregon
- Willamette Stone, survey marker in Oregon
- Willamette Cattle Company, a company formed in Oregon in 1837 to buy cattle in California
- Willamette University, a private institution of higher learning located in Salem
- Willamette High School, a high school in Eugene
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