Entertainment
- Wildcard (G.I. Joe), a fictional character in the G.I. Joe universe
- Wild Card 2, a lottery game in the north-central United States; replaced a similar game called "Wild Card"
- Wild Cards, a series of science fiction/superhero books
- Wild Cards (anthology), the first book in the series
- Wild Card (TV series), a.k.a. Zoe Busiek: Wild Card, a Canadian TV series starring Joely Fisher
- Wild Card (The Rippingtons album), a 2005 album by The Rippingtons
- Wildcard (record label), a minor record label now part with Polydor Records
- Wildcards, a nickname of the most prominent starfighter squadron in Space: Above and Beyond
- A Justice League episode named "Wild Cards"
- Wild Card Stack, a programming block on the Toon Disney TV channel
- Wildcard (Pennywise EP), a 1989 EP by Pennywise
- Wild Card (The Warratahs album), 1990
- Wildcard (album), a 2001 album by Terence Trent D'Arby
- Wildcard (comics), a fictional Marvel character
- An ability from the shin megami tensei persona series that allows the protagonists to summon multiple persona in battle
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