Weis may refer to:
- Weis, a major Australian frozen food company
- Weis Markets, supermarket chain
- WEIS (AM), a radio station (990 AM) licensed to Centre, Alabama, USA
- Weis Manufacturing Company, a NRHP in Monroe, Michigan
- Weis, the middle frog in the Budweiser Frogs advertising campaign
Weis, a German surname, may refer to:
- Al Weis (b. 1938), former Major League Baseball player
- Charlie Weis, former Notre Dame football head coach
- Danny Weis, US guitarist for Iron Butterfly and Rhinoceros
- Frédéric Weis, French professional basketball player
- Heinz Weis (b. 1963), German athlete
- Indira Weis (b. 1979), German actress and singer
- John Ellsworth Weis (1892 - 1962), American painter
- Joseph F. Weis, Jr., US federal judge
- Margaret Weis (b. 1948), US writer
- Melissa Weis (b. 1971), American discus thrower
- Petra Weis (b. 1957), German politician, member of the Bundestag
- Samuel Washington Weis (1870-1956), American painter
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