Walter and Eliza Hall Institute of Medical Research - History

History

The institute was founded in 1915 using funds from a trust established by Eliza Hall following the death of her husband Walter Russell Hall. The institute owes its origin to the inspiration of Harry Brookes Allen, who encouraged the use of a small portion of the charitable trust to found a medical research institute. The vision was for an institute that 'will be the birthplace of discoveries rendering signal service to mankind in the prevention and removal of disease and the mitigation of suffering.’

In April 1915 the new Melbourne Hospital agreed to provide a home for the Walter and Eliza Hall Institute of Research in Pathology and Medicine, as it was then known. A few weeks later, the new institute's director-designate, Gordon Mathison, suffered fatal wounds in the ANZAC Battle of Gallipoli. The floors set aside for the institute in the grounds of the old Melbourne Hospital were given over to the Commonwealth Serum Laboratories in 1918 until a new director could be secured at the cessation of hostilities.

Sydney Patterson was appointed the first director and took up his post in 1919. Patterson resigned and returned to England in 1923. He was followed by Charles Kellaway for the critical years 1923-44. Kellaway formalised research streams, supported aspiring local researchers, built up public benefactions and secured the first Commonwealth grants for the institute's researches. He also oversaw the plans and construction of the first separate institute building adjacent to the new Royal Melbourne Hospital, which opened in 1942. Under Kellaway's directorship, the institute came to achieve international recognition as a centre for excellence in medical research by the outbreak of World War II.

Sir Frank Macfarlane Burnet was the institute director between 1944 and 1965, and he brought the institute to international prominence for virological research, especially influenza, and then for immunology. Such was the nature of Burnet’s achievement that he was awarded the Nobel Prize for Medicine in 1960 with Sir Peter Medawar for the discovery of immunological tolerance.

Sir Gustav Nossal succeeded Burnet as director in 1965, aged 35. Under his stewardship, the institute grew in size and scope, with its scientists making important discoveries in the control of immune system responses, cell cycle regulation and malaria. During this time, the group led by Professor Donald Metcalf discovered and characterised the colony-stimulating factors (CSFs), which have benefited more than 10 million cancer patients worldwide.

Between 1996 and 2009, it was led by Professor Suzanne Cory. Since July 2009, Professor Doug Hilton is the director of WEHI.

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