Vostok (Russian: Восто́к, Orient or East) may refer to:
- Spaceflight
- Vostok programme, Soviet human spaceflight project
- Vostok (spacecraft), a type of spacecraft built by the Soviet Union
- Vostok (rocket family), family of rockets derived from the Soviet R-7 Semyorka ICBM designed for the human spaceflight programme
- Vostok (crater), a crater explored by the Mars rover Opportunity
- Vostok 1, the first human spaceflight
- Other meanings
- Vostok (sloop-of-war), a ship of Faddey Bellingshausen during the First Russian Antarctic Expedition, when Antarctica was discovered
- Vostok Island, located in the south of Kiribati's Line Islands
- Cape Vostok, the west extremity of the Havre Mountains and the northwest extremity of Alexander Island in Antarctic
- Vostok Station, Russian (originally Soviet) Antarctic research station
- Lake Vostok, a subglacial lake in Antarctica, located beneath Vostok Station
- Vostok Subglacial Highlands, an east extension of Gamburtsev Subglacial Mountains in Antarctica
- Vostok Rupes, a mountain chain on planet Mercury
- Vostok traverse, a 1962 Australian expedition across Antarctica
- Vostok watches is a brand of watch, made in Chistopol, Tatarstan, Russia
- Vostok, Primorsky Krai, an urban-type settlement in Krasnoarmeysky District of Primorsky Krai, Russia
- Vostok Bay, bay in south Primorsky Krai, Russia
- Vostok, an Xbox-exclusive map to the game Counter-Strike
- Valentina Vostok, a fictional character by DC Comics
- Vostok (Minsk Metro), a station of Minsk Metro, Minsk, Belarus
- Vostok motorcycles, a motorcycle company
- Vostok Gas, a Bermuda-based oil and gas investment company
- FC Vostok, a Kazakhstani football club
- Special Battalion Vostok, Chechen military unit.
- Vostok Games, a Ukrainian game developer.