VLT may stand for:
- Very Large Telescope, a system of four large (8.2 meter diameter) optical telescopes organized in an array formation, located in northern Chile
- Visible Light Transmittance, the percentage of visible light that passes through a window or material
- Video Lottery Terminal, a gambling machine that allows gamblers to bet on the outcome of a video game
- Vince Lombardi Trophy
- Virtual Line Trunking, a technology used in datacenter class ethernet switches.
- Vestmanlands Läns Tidning, a local daily newspaper in Västerås, Sweden.
- The postcode of Valletta, the capital city of Malta.