Tyre may refer to:
- Tyre, the British spelling of tire, the outer part of a wheel
- Tyre, Lebanon
- Tyre District, Lebanon
- Tyre, New York, United States, a town
- Tyre, an unincorporated community in Austin Township, Sanilac County, Michigan, United States
- Colin Tyre, Scottish lawyer and judge
- Tyre York (1836–1916), U.S. Congressman from North Carolina
- Tyres (mythology), two minor figures in Greek mythology