Recreational Use
A very small number of cases involving non-medical use of antidepressants have been reported over the past 30 years. According to the US government classification of psychiatric medications, TCAs are "non-abusable" and generally have low abuse potential. Several cases of the misuse of amitriptyline alone or together with methadone or in other drug dependent patients and of dothiepin with alcohol or in methadone patients have been reported.
Read more about this topic: Tricyclic Antidepressant