A total ionic strength adjustment buffer (TISAB) is a buffer solution which increases the ionic strength of a solution to a relatively high level. This is important for potentiometric measurements, including ion selective electrodes, because they measure the activity of the analyte rather than its concentration. TISAB essentially masks most chemical interferences in the analyte solution and hence increases the accuracy of the reading.
Other articles related to "total ionic strength adjustment buffer, ionic":
... plays an important role to control the ionic strength and pH of the analyte solution, which may otherwise cause error and inaccuracy ... The activity coefficient depends on the ionic strength of the solution in which the potentiometric measurements are made ... If this calibration is used to calculate the concentration of the analyte in sea water (high ionic strength), significant error is introduced by the ...
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