Tarsus may refer to:
In geography:
- Tarsus, Mersin, ancient and modern city in Turkey
- Tarsus (West Syrian Diocese), a Syrian Orthodox archdiocese, attested between the seventh and thirteenth centuries
- Tarsus Waterfall, on the outskirts of the city
- Berdan River, also known as the Tarsus River, which flows past the city
In biology:
- Tarsus (skeleton), a cluster of articulating bones in each foot
- Tarsus (eyelids), elongated plate of dense connective tissue in each eyelid
- The final segment of an arthropod leg
Other uses:
- Tarsus (1948–1960), a Turkish Maritime Lines ship formerly the USS Harry Lee (APA-10)
- The Tarsus Club, a private men's club of politicians and industrialists
- Tarsus Group plc, an international media company
- Tarsus American College, private high school in Tarsus, Turkey
- Tarsus Academy, a fictional school in the computer game Deus Ex: Invisible War