Spleen - Effects of Removal

Effects of Removal

See also: Asplenia

Surgical removal causes:

  • modest increases in circulating white blood cells and platelets,
  • diminished responsiveness to some vaccines,
  • increased susceptibility to infection by bacteria and protozoa; in particular, there is an increased risk of sepsis from polysaccharide encapsulated bacteria.

A 28-year follow-up of 740 veterans of World War II who had their spleens removed on the battlefield found that those who had been splenectomized showed a significant excess of mortality from pneumonia (6 rather than the expected 1.3) and a significant excess of mortality from ischemic heart disease (4.1 rather than the expected 3) but not from other conditions.

Read more about this topic:  Spleen

Famous quotes containing the words effects and/or removal:

    “The ultimate result of shielding men from the effects of folly, is to fill the world with fools.”
    —Herbert Spencer (1820–1903)

    “Many a reformer perishes in his removal of rubbish,—and that makes the offensiveness of the class. They are partial; they are not equal to the work they pretend. They lose their way; in the assault on the kingdom of darkness, they expend all their energy on some accidental evil, and lose their sanity and power of benefit.”
    —Ralph Waldo Emerson (1803–1882)