Effects of Removal
See also: AspleniaSurgical removal causes:
- modest increases in circulating white blood cells and platelets,
- diminished responsiveness to some vaccines,
- increased susceptibility to infection by bacteria and protozoa; in particular, there is an increased risk of sepsis from polysaccharide encapsulated bacteria.
A 28-year follow-up of 740 veterans of World War II who had their spleens removed on the battlefield found that those who had been splenectomized showed a significant excess of mortality from pneumonia (6 rather than the expected 1.3) and a significant excess of mortality from ischemic heart disease (4.1 rather than the expected 3) but not from other conditions.
Read more about this topic: Spleen
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