Coordinates: 40°47′29″N 17°27′35″E / 40.79139°N 17.45972°E / 40.79139; 17.45972 Speziale, in upper Salento, in the Puglia region of Italy, is a frazione in the municipality of Fasano. It takes its name from an apothecary (it: speziale) who once lived there. Its population was recently measured as 423.
The town has farmhouses and typical Puglian white-painted buildings. Its church, dedicated to St. Maria del Rosario, was built in the early twentieth century. Every year, on the first Sunday of August, the town holds a festival, the Sagra della focaccia.
The surrounding area is notable for large plantations of secular (i.e. long-lived) olive trees. It is a few kilometres from the sea and the hills of the Itria Valley.