Smithton may refer to several places:
- In the United Kingdom
- Smithton, Highland, a community near Culloden in Scotland.
- In Australia
- Smithton, Tasmania
- Smithton Airport
- In the United States
- Smithton, Illinois
- Smithton Township, St. Clair County, Illinois
- Smithton, Missouri
- Smithton Township, Pettis County, Missouri
- Smithton, Pennsylvania
- Smithville, West Virginia, also known as Smithton
- Smithton High School, a high school in Smithton Missouri