Skokomish can refer to:
- Skokomish, Washington, a census-designated place in Mason County, Washington
- Skokomish (tribe), a Native American tribe
- Skokomish language
- Skokomish River
- Sko-ko-mish is an archaic rendering of Sḵwxwú7mesh, the indigenous name of the Squamish people of British Columbia. (NB The Skokomish and Sḵwxwú7mesh are not related other than both being Coast Salish peoples).