Awards and Nominations
| Year | Award | Category | Title of work | Result | Notes |
|---|---|---|---|---|---|
| 2000 | Young Artist Award | Best Performance in a TV Series – Young Ensemble | Freaks and Geeks | Nominated | Shared with cast |
| 2005 | Primetime Emmy Award | Primetime Emmy Award for Outstanding Writing for a Variety, Music or Comedy Program | Da Ali G Show | Nominated | Shared with writing staff |
| 2006 | MTV Movie Award | Best On-Screen Team | 40-Year-Old Virgin, TheThe 40-Year-Old Virgin | Nominated | Shared with Steve Carell, Paul Rudd and Romany Malco |
| 2007 | Satellite Award | Best Performance by an Actor in a Motion Picture – Musical Or Comedy | Knocked Up | Nominated | |
| High Times Stony Award | Stoner of the Year | Won | |||
| 2008 | Canadian Comedy Award | Best Writing (Film) | Superbad | Won | |
| Canadian Comedy Award | Canadian Comedy Person of the Year | Won | |||
| MTV Movie Award | Best Comedic Performance | Knocked Up | Nominated | ||
| MTV Movie Award | Breakthrough Performance | Knocked Up | Nominated | ||
| ShoWest | Comedy Star of the Year | Knocked Up and Superbad | Won | ||
| 2009 | Canadian Comedy Award | Canadian Comedy Person of the Year | Won | ||
| MTV Movie Award | Best Fight | Pineapple Express | Nominated | Shared with James Franco and Danny McBride | |
| Teen Choice Award | Choice Movie Actor: Comedy | Observe and Report and Pineapple Express | Nominated | ||
| 2010 | Kids' Choice Awards | Favorite Voice from an Animated Movie | Monsters vs. Aliens | Nominated | |
| 2012 | Golden Globes | Best Motion Picture – Comedy/Musical | 50/50 | Nominated | Shared w/ Evan Goldberg & Ben Karlin |
| Independent Spirit Awards | Best Feature Film | 50/50 | Nominated | Shared w/ Evan Goldberg & Ben Karlin | |
| Vancouver Film Critics Circle Awards | Best Supporting Actor in a Canadian Film | Take This Waltz | Nominated |
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