History
Investigations using yttrium-90 (90Y, Y-90) and other radioisotopes for cancer treatment began in the 1960s. Reports of the initial use of resin particles of Y-90 in humans were published in the late 1970s. In the 1980s, the safety and feasibility of Y-90 microsphere therapy for liver cancer were validated in a canine model. Clinical trials of Y-90 applied to the liver continued throughout the late 1980s to the 1990s, establishing the safety of the therapy. More recently, larger trials and RCTs have demonstrated safety and efficacy of Y-90 therapy for the treatment of both primary and metastatic liver malignancies.
Read more about this topic: Selective Internal Radiation Therapy
Famous quotes containing the word history:
“The history of all hitherto existing society is the history of class struggles.”
—Karl Marx (1818–1883)
“In history an additional result is commonly produced by human actions beyond that which they aim at and obtain—that which they immediately recognize and desire. They gratify their own interest; but something further is thereby accomplished, latent in the actions in question, though not present to their consciousness, and not included in their design.”
—Georg Wilhelm Friedrich Hegel (1770–1831)
““And now this is the way in which the history of your former life has reached my ears!” As he said this he held out in his hand the fatal letter.”
—Anthony Trollope (1815–1882)