History
Investigations using yttrium-90 (90Y, Y-90) and other radioisotopes for cancer treatment began in the 1960s. Reports of the initial use of resin particles of Y-90 in humans were published in the late 1970s. In the 1980s, the safety and feasibility of Y-90 microsphere therapy for liver cancer were validated in a canine model. Clinical trials of Y-90 applied to the liver continued throughout the late 1980s to the 1990s, establishing the safety of the therapy. More recently, larger trials and RCTs have demonstrated safety and efficacy of Y-90 therapy for the treatment of both primary and metastatic liver malignancies.
Read more about this topic: Selective Internal Radiation Therapy
Famous quotes containing the word history:
“The history of all hitherto existing society is the history of class struggles.”
—Karl Marx (1818–1883)
“History is not what you thought. It is what you can remember. All other history defeats itself.
In Beverly Hills ... they don’t throw their garbage away. They make it into television shows.
Idealism is the despot of thought, just as politics is the despot of will.”
—Mikhail Bakunin (1814–1876)
“All history attests that man has subjected woman to his will, used her as a means to promote his selfish gratification, to minister to his sensual pleasures, to be instrumental in promoting his comfort; but never has he desired to elevate her to that rank she was created to fill. He has done all he could to debase and enslave her mind; and now he looks triumphantly on the ruin he has wrought, and say, the being he has thus deeply injured is his inferior.”
—Sarah M. Grimke (1792–1873)