Scintillation proximity assay, commonly known as SPA, is a type of technology that is used to assay development and biochemical screening which permit the rapid and sensitive measurement of a broad range of biological processes in a homogeneous system. The type of beads that are involved in the SPA are microscopic in size and within the beads itself, there is a scintillant which emits light when it is stimulated. Stimulation occurs when radio-labelled molecules interact and bind to the surface of the bead. This interaction will trigger the bead to emit light, which can be detected using a photometer.
Read more about Scintillation Proximity Assay: Overview, Detail, Advantages Over Previous Methods
Famous quotes containing the words proximity and/or assay:
“Our senses perceive no extreme. Too much sound deafens us; too much light dazzles us; too great distance or proximity hinders our view. Too great length and too great brevity of discourse tends to obscurity; too much truth is paralyzing.... In short, extremes are for us as though they were not, and we are not within their notice. They escape us, or we them.”
—Blaise Pascal (1623–1662)
“The lyf so short, the craft so longe to lerne,
Th’ assay so hard, so sharp the conquerynge,
The dredful joye, alwey that slit so yerne;
Al this mene I be love.”
—Geoffrey Chaucer (1340–1400)