Scintillation proximity assay, commonly known as SPA, is a type of technology that is used to assay development and biochemical screening which permit the rapid and sensitive measurement of a broad range of biological processes in a homogeneous system. The type of beads that are involved in the SPA are microscopic in size and within the beads itself, there is a scintillant which emits light when it is stimulated. Stimulation occurs when radio-labelled molecules interact and bind to the surface of the bead. This interaction will trigger the bead to emit light, which can be detected using a photometer.
Read more about Scintillation Proximity Assay: Overview, Detail, Advantages Over Previous Methods
Famous quotes containing the words proximity and/or assay:
“Reckoned physiologically, everything ugly weakens and afflicts man. It recalls decay, danger, impotence; he actually suffers a loss of energy in its presence. The effect of the ugly can be measured with a dynamometer. Whenever man feels in any way depressed, he senses the proximity of something “ugly.” His feeling of power, his will to power, his courage, his pride—they decline with the ugly, they increase with the beautiful.”
—Friedrich Nietzsche (1844–1900)
“The lyf so short, the craft so longe to lerne,
Th’ assay so hard, so sharp the conquerynge,
The dredful joye, alwey that slit so yerne;
Al this mene I be love.”
—Geoffrey Chaucer (1340–1400)