Retrosynthetic Analysis - Definitions

Definitions

Disconnection
A retrosynthetic step involving the breaking of a bond to form two (or more) synthons.
Retron
A minimal molecular substructure that enables certain transformations.
Retrosynthetic tree
A directed acyclic graph of several (or all) possible retrosyntheses of a single target.
Synthon
An idealized molecular fragment. A synthon and the corresponding commercially available synthetic equivalent are shown below:
Target
The desired final compound.
Transform
The exact reverse of a synthetic reaction; the formation of starting materials from a single product.

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