Function
There are about 1.2 to 1.5 million retinal ganglion cells in the human retina. With about 125 million photoreceptors per retina, on average each retinal ganglion cell receives inputs from about 100 rods and cones. However, these numbers vary greatly among individuals and as a function of retinal location. In the fovea (center of the retina), a single ganglion cell will communicate with as few as five photoreceptors. In the extreme periphery (ends of the retina), a single ganglion cell will receive information from many thousands of photoreceptors.
Retinal ganglion cells spontaneously fire action potentials at a base rate while at rest. Excitation of retinal ganglion cells results in an increased firing rate while inhibition results in a depressed rate of firing.
Read more about this topic: Retinal Ganglion Cell
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