Rayne may refer to:
- Rayne, Essex, England, UK
- Rayne railway station
- Rayne, Aberdeenshire, location of the parish church held by the Archdeacon of Aberdeen in Scotland, UK
- Rayne, Louisiana, U.S.
- Rayne High School
- Rayne Township, Indiana County, Pennsylvania, U.S.
- Rayne (BloodRayne), the protagonist of BloodRayne
Read more about Rayne: People With The Name