RAGE (receptor) - AGE Receptors

AGE Receptors

Besides RAGE there are other receptors which are believed to bind advanced glycation endproducts. However, these receptors could play a role in removal of AGE rather than in signal transduction as it is the case for RAGE. Other AGE receptors are:

  • SR-A (Macrophage scavenger receptor Type I and II)
  • OST-48 (Oligosaccharyl transferase-4) (AGE-R1)
  • 80 K-H phosphoprotein (Proteinkinase C substrate) (AGE-R2)
  • Galectin-3 (AGE-R3)
  • LOX-1 (Lectin-like oxidized low density lipoprotein receptor-1)
  • CD36

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