Risks
According to John Ioannidis, negative papers are most likely to be suppressed when:
- the studies conducted in a field are smaller
- effect sizes are smaller
- there is a greater number and lesser preselection of tested relationships
- there is greater flexibility in designs, definitions, outcomes, and analytical modes
- there is greater financial and other interest and prejudice
- more teams are involved in a scientific field in chase of statistical significance.
Ioannidis further asserts that "claimed research findings may often be simply accurate measures of the prevailing bias".
Read more about this topic: Publication Bias
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