Ptprm

PTPRM

Identifiers Symbols PTPRM; PTPRL1; R-PTP-MU; RPTPM; RPTPU; hR-PTPu External IDs OMIM: 176888 MGI: 102694 HomoloGene: 37694 ChEMBL: 4661 GeneCards: PTPRM Gene EC number 3.1.3.48

Gene Ontology
Molecular function	• protein tyrosine phosphatase activity • transmembrane receptor protein tyrosine phosphatase activity • protein binding • cadherin binding
Cellular component	• cytoplasm • integral to plasma membrane • cell-cell junction • cell-cell adherens junction • lamellipodium • perinuclear region of cytoplasm
Biological process	• negative regulation of endothelial cell proliferation • protein dephosphorylation • homophilic cell adhesion • signal transduction • negative regulation of endothelial cell migration • retina layer formation • negative regulation of angiogenesis • neuron projection development • retinal ganglion cell axon guidance • peptidyl-tyrosine dephosphorylation • response to drug • positive regulation of vasodilation
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 5797 19274 Ensembl ENSG00000173482 ENSMUSG00000033278 UniProt P28827 P28828 RefSeq (mRNA) NM_001105244 NM_008984 RefSeq (protein) NP_001098714 NP_033010 Location (UCSC) Chr 18:
7.57 – 8.41 Mb Chr 17:
66.67 – 67.35 Mb PubMed search

Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene.