PTF may refer to:
- Pedotransfer function, a concept used in soil science
- Phase transfer function, used for the optics of an imaging system
- Police Task Force, former name of the Police Tactical Unit of the Singapore Police Force
- Präzisionsteilefertigung Steffen Pfüller, a producer of high-tech precision parts and assemblies
- Program temporary fix, an IBM locution to designate bug fixes
- Palomar Transient Factory, an astronomical survey program.