Primary Hypertrophic Osteoathropathy - Symptoms

Symptoms

PDP has a lot of visible symptoms. Most important clinical features are: pachydermia (thickening and wrinkling of the skin), furrowing of the face and scalp, periostosis (swelling of periarticular tissue and shaggy periosteal new bone formation of long bones) and digital clubbing (enlargement of fingertips). Other features include excessive sweating, arthralgia and gastrointestinal abnormalities. An overview of all symptoms is provided in table 2.

Table 2. Overview of symptoms

Skin features Pachydermia
Coarse skin
Oily skin
Eczema
Thick hand and foot skin
Leonine facies
Furrowing
Cutis verticis gyrate
Increased secretion of sebum
Sebborheic hyperplasia
Bone features Periostosis
Acroosteolysis
Mylefibrosis
Thick toe and finger bones
Widening of bone formation
Clubbing Digital clubbing
Sweating Hyperhidrosis
Eye features Drooping eyelids
Thick stratum corneum
Joints Arthralgia
Joint effusion
Muscles Muscle discomfort
Hair Decreased facial and pubic hair
Vascular Peripheral vascular stasis
Gastrointestinal involvement Peptic ulcer
Chronic gastritis
Chron’s disease

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