Symptoms
PDP has a lot of visible symptoms. Most important clinical features are: pachydermia (thickening and wrinkling of the skin), furrowing of the face and scalp, periostosis (swelling of periarticular tissue and shaggy periosteal new bone formation of long bones) and digital clubbing (enlargement of fingertips). Other features include excessive sweating, arthralgia and gastrointestinal abnormalities. An overview of all symptoms is provided in table 2.
Table 2. Overview of symptoms
| Skin features | Pachydermia |
|---|---|
| Coarse skin | |
| Oily skin | |
| Eczema | |
| Thick hand and foot skin | |
| Leonine facies | |
| Furrowing | |
| Cutis verticis gyrate | |
| Increased secretion of sebum | |
| Sebborheic hyperplasia | |
| Bone features | Periostosis |
| Acroosteolysis | |
| Mylefibrosis | |
| Thick toe and finger bones | |
| Widening of bone formation | |
| Clubbing | Digital clubbing |
| Sweating | Hyperhidrosis |
| Eye features | Drooping eyelids |
| Thick stratum corneum | |
| Joints | Arthralgia |
| Joint effusion | |
| Muscles | Muscle discomfort |
| Hair | Decreased facial and pubic hair |
| Vascular | Peripheral vascular stasis |
| Gastrointestinal involvement | Peptic ulcer |
| Chronic gastritis | |
| Chron’s disease |
Read more about this topic: Primary Hypertrophic Osteoathropathy
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