PRA is an abbreviation for:
- Panel Reactive Antibody - a measure of the percentage of human antibodies in a transplant candidate's blood
- Paperwork Reduction Act
- the IATA code for the airport in Paraná, Argentina: General Urquiza Airport
- Participatory rural appraisal
- People's Redemption Army, a rebel group in Democratic Republic of the Congo and Uganda
- People's Republic of Albania
- The People's Republic Of Animation, an Australian animation company based in Adelaide
- The People's Republic Of Arlington, a tongue-in-cheek nickname for Arlington County, in the Commonwealth of Virginia
- People's Revolutionary Army, the name of the Army of several countries
- People's Revolutionary Army (Argentina)
- People's Revolutionary Army (Colombia)
- People's Revolutionary Army (Grenada)
- People's Revolutionary Army (Mexico)
- Petrol Retailers Association, part of the Retail Motor Industry Federation (RMIF)
- Physical Review A,a scientific journal, published by the American Physical Society
- Plasma renin activity
- Politieke Recherche Afdeling, Dutch for Political Investigation Branch
- Political Research Associates, a research group in Somerville, Massachusetts, which studies the U.S. political right wing
- Popular Resistance Army, a rebel group in Uganda which later became the National Resistance Army
- Popular Rotorcraft Association, a non-profit aviation interest group founded in 1962 by Igor Bensen
- Positive relative accommodation
- Presidential Records Act
- President of the Royal Academy: see Royal Academy
- Primary rate access, a telecommunications standard
- Primitive recursive arithmetic, a formal system of arithmetic weaker than Peano arithmetic PA
- Probabilistic risk assessment, an engineering safety analysis
- The Professional Rugby Players' Association, the representative body of professional rugby players in England
- Progressive retinal atrophy
- Public relations automation
- Public Roads Administration, a predecessor of the Federal Highway Administration (USA)
- Purported Responsible Address, as specified in RFC 4407; Commonly referenced in SPF
- Saccharopepsin, a yeast proteinase A