PMS2

PMS2

Identifiers Symbols PMS2; HNPCC4; PMS2CL; PMSL2 External IDs OMIM: 600259 MGI: 104288 HomoloGene: 450 GeneCards: PMS2 Gene

Gene Ontology
Molecular function	• DNA binding • single-stranded DNA binding • endonuclease activity • protein binding • ATP binding • ATPase activity • single base insertion or deletion binding • MutSalpha complex binding
Cellular component	• nucleus • mismatch repair complex • MutLalpha complex
Biological process	• ATP catabolic process • mismatch repair • reciprocal meiotic recombination • somatic hypermutation of immunoglobulin genes • somatic recombination of immunoglobulin gene segments • response to drug
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 5395 18861 Ensembl ENSG00000122512 ENSMUSG00000079109 UniProt P54278 A4QPD7 RefSeq (mRNA) NM_000535 NM_008886 RefSeq (protein) NP_000526 NP_032912 Location (UCSC) Chr 7:
6.01 – 6.05 Mb Chr 5:
143.91 – 143.94 Mb PubMed search

Mismatch repair endonuclease PMS2 is an enzyme that in humans is encoded by the PMS2 gene.