Peliosis Hepatis - Disease Associations

Disease Associations

  • Infections: HIV, Bacillary peliosis (caused by genus Bartonella, bacteria responsible for cat-scratch disease which are identified histologically adjacent to the peliotic lesions), Staphylococcus aureus
  • Chronic conditions: End stage renal failure, Kwashiorkor, tuberculosis and other chronic infections.
  • Malignancy: Monoclonal gammopathies (multiple myeloma and Waldenstrom macroglobulinemia), Hodgkin disease, malignant histiocytosis, seminoma, hepatocellular adenoma and hepatocarcinoma,
  • Renal transplants: It can be found in up to 20% patients, can be related to azathioprine or cyclosporine use and may be associated with increased risk of transplant rejection.
  • Drugs and toxins: Corticosteroids, androgens, azathioprine, tamoxifen

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