Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections. Pefloxacin is commonly referred to as a fluoroquinolone (or quinolone) drug and is a member of the fluoroquinolone class of antibacterials. It is an analog of norfloxacin. It is a synthetic fluoroquinolone, belonging to the 3rd generation of quinolones. Pefloxacin is extensively prescribed in France. Pefloxacin has not been approved for use in the United States.
There are no licensed uses for Pefloxacin in the United States, as the FDA has not approved this drug. The licensed use varies in other countries and is quite limited as Pefloxacin is to be considered a drug of last resort when all other antibiotics have failed. There appears to be eight common uses in the adult population and no approved uses in the pediatric population, as well as a variety of veterinary uses (as documented within the package inserts). Pefloxacin interacts with a number of other drugs, a number of herbal and natural supplements, and certain thyroid medications.
Read more about Pefloxacin: History, Licensed Uses, Availability, Trade Names, Mode of Action, Contraindications, Adverse Effects, Interactions, Overdose, Pharmacology, Pharmacokinetics, Dosing, Susceptible Bacteria, Current Litigation, Regulatory History, Antibiotic Misuse and Bacterial Resistance, Social and Economic Impact, See Also, Package Insert Links