Nuclear Pore - Size and Complexity

Size and Complexity

The entire nuclear pore complex (NPC) has a diameter of about 120 nanometers, the diameter of the opening (functional diameter) is about 9 nanometers wide and its "depth" is about 200 nanometers. It had been suggested that the pore can be dilated to around 39 nanometers to allow molecule passage. The molecular mass of the mammalian NPC is about 120 megadaltons and it contains approximately 30 different protein components, each in multiple copies. In contrast, the yeast model organism Saccharomyces cerevisiae is smaller, weighing only 66MDa.

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