Major Intersections
The entire route is in Cattaraugus County.
| Location | Mile | km | Destinations | Notes |
|---|---|---|---|---|
| City of Salamanca | 0.00 | 0.00 | NY 417 | |
| Town of Little Valley | 6.22 | 10.01 | NY 242 east | Eastern terminus of NY 242 / NY 353 overlap |
| Village of Little Valley | 7.43 | 11.96 | NY 242 west | Western terminus of NY 242 / NY 353 overlap |
| Dayton | 23.97 | 38.58 | US 62 |
Read more about this topic: New York State Route 353
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—C. Wright Mills (1916–1962)