Neuraminidase - Reaction

Reaction

There are two major classes of Neuraminidase that cleave exo or endo poly-sialic acids:

  • Exo hydrolysis of α-(2→3)-, α-(2→6)-, α-(2→8)-glycosidic linkages of terminal sialic acid residues
  • Endo hydrolysis of (2→8)-α-sialosyl linkages in oligo- or poly(sialic) acids
exo-α-sialidase
Identifiers
EC number 3.2.1.18
CAS number 9001-67-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures
Gene Ontology
Search
PMC articles
PubMed articles
NCBI Protein search
endo-α-sialidase
Identifiers
EC number 3.2.1.129
CAS number 91195-87-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures
Gene Ontology
Search
PMC articles
PubMed articles
NCBI Protein search

Read more about this topic:  Neuraminidase

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