Muromonab-CD3

Muromonab-CD3 (trade name Orthoclone OKT3, marketed by Janssen-Cilag) is an immunosuppressant drug given to reduce acute rejection in patients with organ transplants. It is a monoclonal antibody targeted at the CD3 receptor, a membrane protein on the surface of T cells. It was the first monoclonal antibody to be approved for clinical use in humans.

Read more about Muromonab-CD3:  History, Indications, Pharmacodynamics and Chemistry, Adverse Effects, Contraindications, Etymology