Multisynthetase Complex Auxiliary Component P38

Multisynthetase Complex Auxiliary Component P38

Identifiers Symbols AIMP2; JTV-1; JTV1; P38 External IDs OMIM: 600859 MGI: 2385237 HomoloGene: 4594 GeneCards: AIMP2 Gene

Gene Ontology
Molecular function	• protein binding
Cellular component	• nucleus • cytosol
Biological process	• tRNA aminoacylation for protein translation • apoptotic process • negative regulation of cell proliferation • gene expression • positive regulation of protein ubiquitination • Type II pneumocyte differentiation
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7965 231872 Ensembl ENSG00000106305 ENSMUSG00000029610 UniProt Q13155 Q8R010 RefSeq (mRNA) NM_006303 NM_001172146 RefSeq (protein) NP_006294 NP_001165617 Location (UCSC) Chr 7:
6.05 – 6.06 Mb Chr 5:
143.9 – 143.91 Mb PubMed search

Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 is an enzyme that in humans is encoded by the AIMP2 gene.

The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. JTV1 is transcribed in the opposite direction compared to HRI and PMS2. The function of the JTV1 gene product is unknown.