MKS may refer to:
- Mutya Keisha Siobhan, an English girl group
- MKS system of units an alternate convention of SI or International System of Measuring Units.
- Lincoln MKS an automobile produced by the Lincoln division of Ford Motor Company.
- MKS Finance a broker of precious metals.
- MKS Incorporated is a software vendor (formerly Mortice Kern Systems), or any of its products:
- MKS Integrity, an application lifecycle management platform.
- MKS Source, a revision control system.
- MKS Toolkit, a Unix-like software environment for Microsoft Windows.
- MKS X/Server, X11 server for Microsoft Windows.
- MKS is a Latin acronym for the labor organization Międzyzakładowy Komitet Strajkowy in Poland. It translates Inter-Enterprise Strike Committee
- MKS or Mario Kart series is an original 'racing game' with character Mario Kart from Nintendo.
- .mks, a file extension for Matroska Multimedia Container.