Masterson may refer to:
People:
- Bat Masterson, gunfighter, lawman, sports writer
- Chase Masterson, actor
- Christopher Masterson, actor
- Danny Masterson, actor, older brother of Christopher Masterson
- Fay Masterson, actress
- Guy Masterson, film director
- James F. Masterson, American psychiatrist
- Justin Masterson, American baseball player
- Kelly Masterson, screenwriter.
- Kleber S. Masterson, Vice Admiral U.S. Navy
- Mary Stuart Masterson, actor
- Michael M. Masterson, Chairman and CEO, Sammons Financial Group
- Paul Masterson, music producer
- Robert Benjamin (Ben) Masterson (1853-1931), cattleman
- Thomas G. Masterson (c. 1813–1884), attorney and businessman
- Valerie Masterson English opera singer
- Wally Masterson, baseball pitcher
- Wayne Masterson, British scientist
Places:
- United States:
- Masterson, community, Carson County, Texas (35°24′40″N 101°37′10″W / 35.41111°N 101.61944°W / 35.41111; -101.61944)
- Masterson, community, Moore County, Texas (35°38′09″N 101°57′36″W / 35.63583°N 101.96°W / 35.63583; -101.96)
- Masterson Lake, reservoir, Tyler County, Texas (30°41′02″N 94°23′15″W / 30.68389°N 94.3875°W / 30.68389; -94.3875)
- Masterson Lake Dam, dam, Tyler County, Texas (30°41′00″N 94°23′12″W / 30.6833333°N 94.38667°W / 30.6833333; -94.38667)
- Masterson Mill, community, Lawrence County, Alabama (34°32′19″N 87°17′00″W / 34.53861°N 87.2833333°W / 34.53861; -87.2833333)
- Masterson Mill Lake Dam, dam, Lawrence County, Alabama (34°32′42″N 87°16′12″W / 34.545°N 87.27°W / 34.545; -87.27)
- Masterson Oil Field, oilfield, Pecos County, Texas (31°07′49″N 102°37′53″W / 31.13028°N 102.63139°W / 31.13028; -102.63139)
- Mastersonville, community, Lancaster County, Pennsylvania (40°11′48″N 76°29′13″W / 40.19667°N 76.48694°W / 40.19667; -76.48694)
- The Masterson Institute For Psychoanalytic Psychotherapy, New York City
Other:
- Winifred Masterson Burke and the Winifred Masterson Burke Medical Research Institute