List of Important Publications in Medicine - Recent Studies

Recent Studies

Mortality in relation to smoking: 50 years' observation on male British doctors

Authors: R. Doll, R. Peto, J. Boreham, I. Sutherland
Publication data: BMJ 2004;328:1519–33.
Description: This is the British doctors study. A prospective clinical trial which ran from 1951 to 2001, and in 1956 provided convincing statistical evidence that tobacco smoking increases the risk of lung cancer.
Importance: Impact

Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study

Authors: The Scandinavian Simvastatin Survival Study Group.
Publication data: Lancet 1994;344:1383–1389
Description: The Scandinavian Simvastatin Survival Study (also known under the abbreviation 4S) is a multicenter clinical trial that was performed in the 1990s in Scandinavia. The objective of the study was to assess the effect of a cholesterol-lowering drug called simvastatin on mortality and morbidity in group of 4444 patients with coronary heart disease, aged between 35 and 70 years. The patients presented with moderate hypercholesterolemia between 5.5 and 8.0 mmol/L. The results of the trial showed that simvastatin had a lowering effect on mortality and morbidity of patients suffering from coronary heart disease.
Importance: Impact

Heart Protection Study

Authors: Medical Research Council
Online version: Research site
Description: The Heart Protection Study is a large randomized controlled trial by the Medical Research Council (MRC) in the United Kingdom. It studies the use of statin (simvastatin 40 mg) medication and vitamin supplementation (vitamin E, vitamin C and beta carotene) in patients that are at risk for cardiovascular disease.
Importance: Impact

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Famous quotes containing the word studies:

    What happiness did poor Mother’s studies bring her? It is the melancholy tendency of such studies to separate people from their friends and neighbors and fellow creatures in whom alone lies one’s happiness.
    Mary Potter Playne (c. 1850–?)

    These studies which stimulate the young, divert the old, are an ornament in prosperity and a refuge and comfort in adversity; they delight us at home, are no impediment in public life, keep us company at night, in our travels, and whenever we retire to the country.
    Marcus Tullius Cicero (106–43 B.C.)