Medications
Reduced libido is also often iatrogenic and can be caused by many medications, such as hormonal contraception, SSRIs and other antidepressants, antipsychotics, opioids and beta blockers. In some cases iatrogenic impotence or other sexual dysfunction can be permanent, as in post-SSRI sexual dysfunction (PSSD).
Testosterone is one of the hormones controlling libido in human beings. Emerging research is showing that hormonal contraception methods like "the pill" (which rely on estrogen and progesterone together) are causing low libido in females by elevating levels of sex hormone binding globulin (SHBG). SHBG binds to sex hormones, including testosterone, rendering them unavailable. Research is showing that even after ending a hormonal contraceptive method, SHBG levels remain elevated and no reliable data exists to predict when this phenomenon will diminish.
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