Lead time bias is the bias that occurs when two tests for a disease are compared, and one test (the new, experimental one) diagnoses the disease earlier, but there is no effect on the outcome of the disease—it may appear that the test prolonged survival, when in fact it only resulted in earlier diagnosis when compared to traditional methods. It is an important factor when evaluating the effectiveness of a specific test.
Read more about Lead Time Bias: Relationship Between Screening and Survival
Famous quotes containing the words lead, time and/or bias:
“A quibble is to Shakespeare what luminous vapours are to the traveller: he follows it at all adventures; it is sure to lead him out of his way and sure to engulf him in the mire.”
—Samuel Johnson (1709–1784)
“To be faced with what so-and-so’s mother lets him do, or what the teacher said in class today or what all the kids are wearing is to be required to reexamine some part of our belief structure. Each time we rethink our values we reaffirm them or begin to change them. Seen in this way, parenthood affords us an exceptional opportunity for growth.”
—Ruth Davidson Bell (20th century)
“The solar system has no anxiety about its reputation, and the credit of truth and honesty is as safe; nor have I any fear that a skeptical bias can be given by leaning hard on the sides of fate, of practical power, or of trade, which the doctrine of Faith cannot down-weigh.”
—Ralph Waldo Emerson (1803–1882)