LCN2
Gene Ontology | |
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Molecular function | • protease binding • transporter activity • iron ion binding • small molecule binding • protein homodimerization activity |
Cellular component | • extracellular region • extracellular space • cytoplasm • cytosol |
Biological process | • ion transport • apoptotic process • response to virus • response to herbicide • positive regulation of gene expression • siderophore transport • positive regulation of cell projection organization • cellular response to nutrient levels • response to drug • regulation of apoptotic process • innate immune response • protein homotrimerization • cellular response to hydrogen peroxide • cellular response to lipopolysaccharide • cellular response to interleukin-1 • cellular response to tumor necrosis factor |
Sources: Amigo / QuickGO |
130.91 – 130.92 Mb
32.38 – 32.39 Mb
Lipocalin-2 (LCN2), also known as oncogene 24p3 or neutrophil gelatinase-associated lipocalin (NGAL), is a protein that in humans is encoded by the LCN2 gene. NGAL is involved in innate immunity by sequestrating iron that in turn limits bacterial growth. It is expressed in neutrophils and in low levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts. NGAL is used as a biomarker of kidney function.
Read more about LCN2: Function, Laboratory Measurement, History