Prominent people with the surname Kopp include:
- Carlo Kopp, Australian defence analyst
- Elisabeth Kopp (born 1936), Swiss politician
- Emil Kopp (1817–1875), French chemist
- Georg von Kopp (1837–1914), German cardinal
- Georges Kopp (1902–1951), Belgian commander of Republican forces in the Spanish Civil War
- Hal Kopp (1909–1998), American college football coach
- Hermann Kopp (born 1954), German composer and musician
- Hermann Franz Moritz Kopp (1817–1892), German chemist
- James Charles Kopp (born 1954), American murderer
- Joseph Eutych Kopp (1793–1866), Swiss antiquarian (see Kopp, Joseph Eutychius, Encyclopedia Americana (1920)
- Magdalena Kopp (born 1948), member of the Frankfurt Revolutionary Cells (RZ), wife and accomplice of Carlos the Jackal
- Nancy K. Kopp (born 1943), American politician
- Quentin L. Kopp (born 1930), American politician
- Sheldon Kopp (1929–1999), American psychotherapist
- Stephen J. Kopp (born 1950/51), American university president
- Wendy Kopp (born 1967), president and founder of Teach For America